{ "metadata": { "name": "", "signature": "sha256:4f05d1a974559a0a9218f4ac7951812cc559753df63ce898b7d228d1a7c7d1ff" }, "nbformat": 3, "nbformat_minor": 0, "worksheets": [ { "cells": [ { "cell_type": "code", "collapsed": false, "input": [ "http://www.nature.com/nature/journal/v490/n7418/full/nature11413.html" ], "language": "python", "metadata": {}, "outputs": [] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\n", "k-mer-based analysis of the oyster genome showed that ~35% of 17-mers had at least two identical copies in the genome, suggesting an abundance of repetitive sequences (Supplementary Fig. 1). Similarly, homology searching and ab initio prediction found 202\u2009Mb (36% of the genome) in repetitive sequences (Supplementary Text C2 and Supplementary Table 8). Over 62% of the detected repeats could not be assigned to known categories, reflecting the paucity of genomic information from molluscs22. Large numbers of transposase (359) and reverse-transcriptase (779) gene fragments were detected; over 96% of these had detectable transcripts (Supplementary Fig. 8). Alignment of the wild sequence against the assembly identified 20,605 deletions (>100\u2009bp), over 80% of which overlapped with detected transposable elements, suggesting that transposable elements may have an active role in shaping genome variation. Using MITE-hunter23, we detected 157,007 copies of miniature inverted-repeat transposable elements (MITEs), accounting for a remarkable 8.82% of the genome (Supplementary Text C2.3 and Supplementary Table 9). Pair-wise comparisons show extremely low sequence divergence in some MITE families (Supplementary Fig. 9), indicating that they may still be active.\n" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A007F.png\"/" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A009F.png\"/" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A00B7.png\"/" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A00EE.png\"/" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A011A.png\"/" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A0135.png\"/" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A014B.png\"/" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A01C2.png\"/" ] }, { "cell_type": "markdown", "metadata": {}, "source": [ "\"www_nature_com_nature_journal_v490_n7418_extref_nature11413-s1_pdf_1A3A01EA.png\"/" ] }, { "cell_type": "code", "collapsed": false, "input": [], "language": "python", "metadata": {}, "outputs": [] } ], "metadata": {} } ] }