Beyond the Genome: Epigenetic Regulation in the Pacific Oyster

Mackenzie Gavery & Steven Roberts, School of Aquatic & Fishery Sciences, UW

Data Presented at PAGXXI

Presentation
Aquaculture Workshop
9:15 AM W041
Epigentic Landscapes In A Marine Mollusc: What DNA Methylation Patterns Tell Us About Gene Regulation In The Pacific Oyster (Crassostrea gigas)

Bisulfite Data tracks available at
http://genefish.wikispaces.com/crassostreome

Software Used
BS-MAP - http://code.google.com/p/bsmap/
Galaxy - http://galaxyproject.org/
methyl-kit - http://code.google.com/p/methylkit/
CLC Genomics Workbench -


Publications
Roberts SB and Gavery MR (2012) Is there a relationship between DNA methylation and phenotypic plasticity in invertebrates? Frontiers in Physiology. 2:116. doi:10.3389/fphys.2011.00116

Gavery MR* and Roberts SB. (2012) Characterizing short read sequencing for gene discovery and RNA-Seq analysis in //Crassostrea gigas//. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 7:2 94-99 June 2012. doi:10.1016/j.cbd.2011.12.003

Gavery M* and Roberts SB. (2010) DNA methylation patterns provide insight into epigenetic regulation in the Pacific oyster (//Crassostrea gigas//) BMC Genomics 11:483 doi:10.1186/1471-2164-11-483

Methylation Enhanced Random Variation (MERV) Theory

Theory on function of DNA methylation in oysters

(Described in Roberts and Gavery - 2012)

---

Poster (PDF link)

---

Useful Links:

• Public Sigenae Contig Browser: Oyster - GigasDatabase
• Roberts Lab web page
• methylation tag in mgavery's Delicious

---

Contact us